Prebiotics, Probiotics, Paraprobiotics, Postbiotics?! HELP!
- Diana Stafford, MD
- Oct 23, 2023
- 2 min read

With all the terminology out there, it can be confusing to figure out what pre-, pro-, or post- product would be helpful and what might actually cause more problems. Here's a review of the terminology:
Prebiotics: Prebiotics are non-digestible dietary fibers and compounds that serve as food for beneficial bacteria in the gut. These substances, often found in foods like garlic, onions, and certain types of fiber, promote the growth and activity of probiotics. Prebiotics play a crucial role in maintaining a healthy gut microbiome by providing nourishment for the probiotic bacteria, helping them flourish and perform their beneficial functions.
Probiotics: Probiotics are live microorganisms, primarily bacteria and sometimes yeast, that offer various health benefits when consumed in adequate amounts. These "good" bacteria are naturally present in fermented foods like yogurt, kefir, and sauerkraut, as well as in dietary supplements. Probiotics are known to promote digestive health, boost the immune system, and help maintain a balanced gut microbiome by increasing the population of beneficial bacteria and crowding out harmful ones.
Paraprobiotics: Paraprobiotics are non-viable (dead) microorganisms or their components that can still confer health benefits when consumed. Unlike live probiotics, paraprobiotics do not replicate in the gut but can exert immunomodulatory and anti-inflammatory effects. These non-viable microbial components, such as cell wall fragments or inactivated bacteria, have garnered interest for their potential to support gut health and immunity without the concerns associated with live bacteria.
Postbiotics: Postbiotics are the metabolic byproducts of probiotic bacteria's activity, such as short-chain fatty acids, peptides, and other bioactive compounds. These substances are generated during the fermentation of prebiotics by probiotics in the gut. Postbiotics are thought to play a significant role in gut health and overall well-being. They can have anti-inflammatory, antioxidant, and immune-modulating properties, contributing to the overall balance of the gut microbiome and supporting various aspects of health.
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